The study team first manipulated the concentration of BMPs in the spinal-cord of the chicken embryo. They discovered that a particular kind of BMP generally creates particular types of sensory interneurons, from the concentration from the BMP regardless. The team discovered that raising the focus of a particular kind of BMP can make even more of the same types of sensory interneuron, but won’t build a different group of sensory interneuron completely. The team then applied these findings to mouse embryonic stem cells in laboratory meals.